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ELIBIO

Présentation

La rencontre de l’Electronique et de la Biologie avait déjà eu lieu au laboratoire IMS, dans l’ancienne équipe ISN(*) dont les circuits et systèmes imitaient les neurones et réseaux de neurones, au point de pouvoir parfois communiquer avec des neurones vivants. L’équipe ELIBIO a été créée le 1er janvier 2010, pour faire émerger cette thématique spécifique d’interaction Electronique-Vivant.

ELIBIO explore les propriétés et applications de l’interface vivant-électronique, afin de mieux connaître certains mécanismes d’interaction biophysique ou de proposer de nouveaux dispositifs thérapeutiques. Elle repose sur l’établissement d’une communication bi-directionnelle entre tissus biologiques et circuits électroniques, in vitro ou in vivo, dans le sens de l’acquisition de bio-signal ou celui de la stimulation électrique.

Les principaux objectifs scientifiques sont :

  • L’étude des mécanismes d’interaction bio-physiques
  • L’innovation de l’interface bioélectronique en elle-même, la recherche de nouveaux biocapteurs
  • Le développement de nouveaux outils d’analyse bio-électrique
  • Le développement de nouveaux dispositifs de stimulation thérapeutique

(*)Ingénierie des Systèmes Neuromorphiques

Membres
           
BORNAT Yannick, MCU, Responsable d'équipe OLCOMENDY Loïc Doctorant DEGACHE Amélie, Doctorante   LEWIS Noëlle, PR  
           
N'KAOUA Gilles, IR Louis REGNACQ, Stagiaire M1 RENAUD Sylvie, PR   Alexis BIDAULT, Stagiaire M2  

Compétences

Si les applications sont souvent tournées vers le domaine de la Santé, les méthodes relèvent plutôt du domaine des STIC :

  • Modélisation de l’Interface Electronique/Vivant
  • Enregistrement, extraction de biomarqueur
  • Calcul Embarqué temps réel
  • Circuits intégrés analogiques et mixtes

Les circuits et systèmes développés sont testés dans le cadre d'expérimentations in vitro ou in vivo.

  • Pour plus de détails sur cibles thérapeutiques et projets de l’équipe : voir la rubrique PROJETS
  • Pour plus de détails sur les dispositifs développés : voir la rubrique GALERIE
PROJETS

IsletChip (2014 - 2017)

Grant support: ANR (Agence Nationale de la Recherche, France) and DGOS (Direction Générale de l'Offre de Soins, France)

Type 1 diabetes concerns some 30 million patients. Transplantation represents one therapeutic choice in patients with serious progressive complications. Currently no method has been established to evaluate the quality of donor islets within the short time span prior to transplantation. IsletChip bridges this important gap in a multidisciplinary approach (diabetology-transplantation medicine/biology-electrophys./microelectronics) from CNRS research groups, clinical groups in France (Grenoble, Montpellier) and in Switzerland (Geneva). The project develops a novel bio-sensing approach (extracellular recordings of islets on MEAs), real-time data filtering and time-frequency analysis. The project addresses technological, biological and signal processing challenges that will be of benefit for other applications (e.g. rehabilitation of neuronal motor control, control of stem cell differentiation). Our approach may ultimately also serve as sensor in an artificial pancreas. 

CEnAVex (2013-2016)

Grant support: ANR (Agence Nationale de la Recherche, France) and NIH (National Institutes of Health, USA)

Approximately 270,000 Americans and 20,000 French are survivors of traumatic spinal cord injury (SCI). The cervical cord is the most common site of injury (54%) and people with cervical SCI can have partial or complete loss of ventilatory control. Most people with SCI that require ventilation management are initially supported with positive pressure-mechanical ventilation, which is associated with significant discomfort and can lead to respiratory diseases and prevent optimal recovery. Alternatively, ventilation can be achieved by diaphragmatic pacing by electrical phrenic nerve stimulation. More recently, intramuscular stimulation of multiple respiratory muscles has been proposed as a viable less surgically invasive approach. The open-loop stimulation strategy currently utilized for pacing has major limitations including the need for manual stimulation parameter tuning, and inability to alter stimulation parameters on muscle fatigue or changing metabolic demand. 

The CENAVEX project proposes the design, development and prototype realization of a novel closed-loop control system that utilizes the computational power of spike-based neuromorphic hardware to adaptively control dynamic processes in biological systems. It will specifically address the challenge of simultaneously adapting the rhythm and pattern of oscillatory drive to achieve effective and efficient control of complex biological functions. The work will focus on the specific problem of controlling ventilation in individuals with high-level SCI by electrically stimulating the motoneurons that drive respiratory musculature. 

To accomplish our objectives we will develop a lung-respiratory muscles computational model and test the abilities of the CENAVEX system, implement the control scheme in software for real-time computer-based control of ventilation in anesthetized intact rodents and those with chronic cervical incomplete SCI, and implement the scheme in neuromorphic hardware with spiking networks, synaptic learning and bio-interface hardware for standalone system assessment in rodents. Successful completion of the proposed project will pave the path for translation to an innovative respiratory pacing system capable of allowing adequate ventilation in people with SCI with impaired respiratory control, taking into account non-linear properties of muscle activation, muscle fatigue, and metabolic demand of the individual.

The Human Brain Project (2013-2023)

Grant support: European Union (Flagship projects - Future Emerging Technologies)

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding will lead to fundamentally new computing technologies, transform the diagnosis and treatment of brain diseases, and provide profound insights into our humanity. Today, for the first time, exponential improvements in the capabilities of modern ICT open up new opportunities to investigate the complexity of the brain. The goal of the Human Brain Project (HBP) is thus to build an integrated ICT infrastructure enabling a global collaborative effort to address this grand challenge, and ultimately to emulate the computational capabilities of the brain. The infrastructure will consist of a tightly linked network of six ICT platforms, which, like current large-scale physics facilities, will operate as a resource both for core HBP research and for external projects, chosen by competitive call. The HBP will drive innovation in ICT, creating new technologies for i) interactive supercomputing, visualisation and big data analytics; ii) federated analysis of globally distributed data; iii) simulation of the brain and other complex systems; iv) objective classification of disease; v) scalable and configurable neuromorphic computing systems, based on the brain’s principles of computation and cognition and its architectures. Expected outputs include simulations of the brain that reveal the chains of events leading from genes to cognition; simulations of diseases and the effects of drugs; early diagnoses and personalised treatments; and a computing paradigm that overcomes bottlenecks in power, reliability and programmability, captures the brain’s cognitive capabilities, and goes beyond Moore’s Law. Overall, the HBP will help to reach a unified understanding of the brain, reduce the economic and social burden of brain disease, and empower the European pharmaceutical and computing industries to lead world markets with enormous potential for growth. 

IMS Bordeaux is in charge of organizing over HBP consortium workshops, schools, on-line training and conferences:

  • Multidisciplinary workshops on HBP-related research topics
  • Platform training workshops
  • Summer Schools
  • Annual student conference

Partners: 
87 institutions (EU and non-EU)

Diaβetachip (2013-2015)

Hybrid Bioelectronics Sensors as Novel Devices for Use in Diabetology

Based on our expertise and proof of concept (see below), we propose to develop stepwise a new cell based-technology combining primary islet cells cultured on multi-electrode arrays (MEAs) and digital on-chip computation for real-time analysis (providing smart MEAs). This ensures rapid diagnostics and avoids storage of extremely large amounts of data generated by high-frequency recordings. Microelectrode arrays and extracellular recordings allow long-term measurements (in our hands for more than a week) in contrast to other techniques (optical, patch) and such set-ups are per se relatively easy to miniaturize. Our arrangement of smart MEAs will serve:

  • First as a device for automated functional islet screening within the granting period for pre-transplantation quality tests, drug and toxicology tests, real-time analysis during regeneration of islet cells from stem cells: the Diaßchip device.
  • In the long-term we plan to extend this device to a bio-microelectronic hybrid sensor of insulin demand: the Diaßsensor product.

Partners: 
University hospital of Bordeaux 
CBMN (UMR 5248)

BIODIA (2012-2014)

Biotechnologies for diabetes therapy

Using cultured pancreatic islets (or islet cells) as sensor, microelectrodes to record the sensor signal and active microelectronic devices to decode on-line the sensor signal, BIODIA aims now to provide the following two items:

  • An external sensor for automatic screening of glucose responses and the effect of drugs and toxic compounds hereon (to be used in screening for compounds or during stem cell differentiation).
  • An external sensor detecting the demand in insulin as the base for the further development of a sensor commanding an insulin pump and functioning in a closed loop configuration.

Beyond the granting period, the closed loop will be developed further to provide a sensor for continuous on-line monitoring and automated signal interpretation (drug/toxicology screening) in animals (48 months) and finally an implantable sensor operating in a closed-loop with a delivery device in man. 

Partners: 
J. Lang, CBMN (UMR 5248) 
V. Ravaine, ISM (UMR 5255)

HYRENE (2011-2014)

HYRENE is a fundamental research project aiming at the development of innovative technologies : hybrid systems connecting artificial and biological neural networks. 

One goal of this project is to couple a whole organ (mouse spinal cord) with a hardware networks in order to restore the organ functional activity after a lesion. Further perspectives are the development of smart “neuroelectronic” interfaces for functional rehabilitation. Population aging all around the world raises a societal issue due to the associated increase in neurodegenerative diseases. 
One therapeutic approach to treat resulting functional deficiencies is to propose neural prosthesis based on neuro-electronic implants. In recent years, technological advances in the field of micro- and nano-electronics has led to the development of new instrumentation tools for the exploration of the central nervous system, making use of dedicated interfaces between microelectronics and live neural networks. This field of research has strongly developed since 2000, especially with the emergence of brain-machine interfaces. These interfaces, which are now tested in humans, process brain signals recorded with microelectrode arrays to turn them into command signals for the control of external devices (robotic arms, computers…). 
However, to date, such interfaces remain mainly monodirectional, with no information delivered back to the network. The current challenge is to achieve bidirectional neuro-electronic interfaces, establishing a true dynamic communication between live neural networks and electronic systems. Especially, electronic systems connected to neural networks with existing technologies do not include embedded intelligence. 
The technical approach defined for HYRENE is to couple live large-scale neural networks and artificial neural networks embedded in analog and mixed integrated electronics and endowed with adaptive capabilities (synaptic plasticity). This hybrid coupling will use dedicated microelectrode arrays to record and electrically stimulate live neural networks, with a specific emphasis on stimulation localization. The system including the artificial and living neural networks will form a closed loop with a regulated feedback. The artificial neural networks will implement conductance-based neuron and synapse models, controlled by plasticity rules like STDP (spike-timing dependent plasticity). 
Dedicated integrated electronics will be designed to implement the communication channels between the living and artificial networks: signal conditioning for the biological signals (from living to artificial) and adapted coding of the artificial neurons events (from artificial to living). In this project, integration between physics (electronic engineering, Microsystems) and biology (integrative neuroscience) is mandatory. 

All 3 partners rely on their large experience in multi-disciplinary collaborative projects at national and international levels. This project is expected to generate scientific advances:

  • in the field of information science: by the design of embedded self-organized artificial neural networks, able to communicate in real time with entire biological networks.
  • in the field of life science : a tool to develop and test efficient strategies for spinal cord rehabilitation.
GALERIE

SHIVA

SHIVA 2       Date : 2014
Designer : Florian Kölbl
Technology : CMOS AMS 0.35μm HV
Size : 2100*1550μm without pads
Description : SHIVA (Stimulator with High voltage compliance for In Vivo/vitro Applications) is an ASIC designed to provide current mode electrical stimulation of biological tissues in different contexts. The design principle is based on a scale effect on electrode impedances, so that one chip can provide from 1 to 8 channels that can stimulate micro or macro electrode(s). These chip can also be combined to provide stimulation on more than 8 channels setups.
 

SEPIA

SEPIA 2   Date : 2013
Designer : Florian Kölbl
Size : 14*30 mm
Description : SEPIA is an embedded stimulator for chronic Deep Brain Stimulation on small rodents. The circuit is placed on a plastic support implanted over the rodent's skull by surgery. The circuit, its batteries and packaging weight less than 14 g and can be implanted on the animal letting him free to move in the experimental area. Stimulation waveform can also be changed by physiologists to test different stimulation strategies, study the involved mechanisms and evaluate DBS sides effects.
 

MultiMed

multimed pitit   Date : 2012
Designer : Jean-Baptiste Floderer
Description : MultiMed is a digital platform dedicated to bioelectric signal treatments. This FPGA based system is able to amplify, register and treat in real time 64 channels of a Multi-Electrode Array. Spike detection and slow wave analysis can be executed for multiple application fields like in vitro neural network recording, ex-vivo spinal cord monitoring and pancreatic cell activity analysis. The graphical user interface (VGA) allows the real time display of the data and the modification of the configuration parameters of this system.
 

OSLO

layoutCircuit2 Guillaume Arnaud   Process : CMOS AMS 0.35μm
Date : 07/2011
Size : 1600*1600μm2 without pads
Designer : Guillaume Arnaud
Description : The ASIC "OSLO" is dedicated to the on-line detection of neural action potential (spikes) that convey information for in vitro excitable cells. OSLO computes in analog mode a detection threshold of the spikes; this threshold is servoed to the standard deviation of the input signal (neural signal). OSLO output stage encodes spike events in asynchronous binary mode. OSLO is a test device; further prototypes should be embedded in microsystems or implants.
 

MINUS

Minus small   Process : AMS 0.35um 2P4M CMOS process
Date : 07/2010
Size : 3000 * 3000 μm2 without pads
Designer : Adeline Zbrzeski
Description :M edicalI nterface forN eU ronalS timulation is dedicated to acquisition of low-amplitude neuronal signals, and adapted stimulation. The device includes different amplifiers and filters for test and characterization.
 
Publications

Total : 169

Articles dans des revues avec comité de lecture → 38 Voir

2018


Hubble PanCET: an isothermal day-side atmosphere for the bloated gas-giant HAT-P-32Ab
Nikolov, N. ; Sing, D. ; Goyal, J. ; Henry, G. ; Wakeford, H. ; Evans, M. ; López-Morales, M. ; García Muñoz, A. ; Ben-Jaffel, L. ; Sanz-Forcada, J. ; Ballester, G. ; Kataria, T. ; Barstow, J. ; Bourrier, V. ; Buchhave, A. ; Cohen, O. ; Deming, D. ; Ehrenreich, D. ; Knutson, H. ; Lavvas, P. ; Lecavelier Des Etangs, A. ; Lewis, N. ; Mandell, M. ; Williamson, M.
Dans : Monthly Notices of the Royal Astronomical Society
https://hal.univ-reims.fr/hal-01804858

2017


Biomimetic neural network for modifying biological dynamics during hybrid experiments
Ambroise, Matthieu ; Buccelli, Stefano ; Grassia, Filippo ; Pirog, Antoine ; Bornat, Yannick ; Chiappalone, Michela ; Levi, Timothée
Dans : Artificial Life and Robotics
https://hal.archives-ouvertes.fr/hal-01567477

Simultaneous monitoring of single cell and of micro-organ activity by PEDOT:PSS covered multi-electrode arrays
Koutsouras, Dimitrios ; Perrier, Romain ; Villarroel Marquez, Ariana ; Pirog, Antoine ; Pedraza, Eileen ; Cloutet, Eric ; Renaud, Sylvie ; Raoux, Matthieu ; Malliaras, George G. ; Lang, Jochen
Dans : Materials Science and Engineering: C
https://hal.archives-ouvertes.fr/hal-01578781

In vitro and in vivo biostability assessment of chronically-implanted Parylene C neural sensors
Lecomte, Aziliz ; Degache, Amélie ; Descamps, Emeline ; Dahan, Lionel ; Bergaud, Christian
Dans : Sensors and Actuators B: Chemical
https://hal.laas.fr/hal-01528604

2016


Generation of Locomotor-Like Activity in the Isolated Rat Spinal Cord Using Intraspinal Electrical Microstimulation Driven by a Digital Neuromorphic CPG
Joucla, Sébastien ; Ambroise, Matthieu ; Levi, Timothée ; Lafon, Thierry ; Chauvet, Philippe ; Saïghi, Sylvain ; Bornat, Yannick ; Lewis, Noëlle ; Renaud, Sylvie ; Yvert, Blaise
Dans : Frontiers in Neuroscience
https://hal.archives-ouvertes.fr/hal-01562686

An Embedded Deep Brain Stimulator for Biphasic Chronic Experiments in Freely Moving Rodents
Kolbl, FLorian ; N'Kaoua, Gilles ; Naudet, Frederic ; Berthier, Florent ; Faggiani, Emilie ; Renaud, Sylvie ; Benazzouz, Abdelhamid ; Lewis, Noelle
Dans : IEEE Transactions on Biomedical Circuits and Systems
https://hal.archives-ouvertes.fr/hal-01347597

Theoretical study and optimisation of a standard deviation estimator circuit for adaptive threshold spike detection
Rummens, François ; Ygorra, Stéphane ; Renaud, Sylvie ; Lewis, Noëlle
Dans : International Journal of Circuit Theory and Applications
https://hal.archives-ouvertes.fr/hal-01347474

Bio-Inspired Controller on an FPGA Applied to Closed-Loop Diaphragmatic Stimulation
Zbrzeski, Adeline ; Bornat, Yannick ; Hillen, Brian ; Siu, Ricardo ; Abbas, James ; Jung, Ranu ; Renaud, Sylvie
Dans : Frontiers in Neuroscience
https://hal.archives-ouvertes.fr/hal-01347466

2015


Slow potentials encode intercellular coupling and insulin demand in pancreatic beta cells
Lebreton, Fanny ; Pirog, Antoine ; Belouah, Isma ; Bosco, Domenico ; Berney, Thierry ; Meda, Paolo ; Bornat, Yannick ; Catargi, Bogdan ; Renaud, Sylvie ; Raoux, Matthieu ; Lang, Jochen
Dans : Diabetologia
https://hal.archives-ouvertes.fr/hal-01347716

Guiding pancreatic beta cells to target electrodes in a whole-cell biosensor for diabetes
Pedraza, Eileen ; Karajić, Aleksandar ; Raoux, Matthieu ; PERRIER, Romain ; Pirog, Antoine ; Lebreton, Fanny ; Arbault, Stéphane ; Gaitan, Julien ; Renaud, Sylvie ; Kuhn, Alexander ; Lang, Jochen
Dans : Lab on a Chip
https://hal.archives-ouvertes.fr/hal-01347681

2014


O51 Diaβchip : un nouveau biosenseur hybride de l’état physiologique des îlots de Langerhans et de la demande en insuline
Lebreton, F. ; Raoux, M. ; Bornat, Y. ; Quotb, A. ; Floderer, J. ; Gaitan, J. ; Catargi, B. ; Renaud, S. ; Lang, J.
Dans : Journal of Diabetes & Metabolism
https://hal.archives-ouvertes.fr/hal-01648715

2013


In vitro large-scale experimental and theoretical studies for the realization of bi-directional brain-prostheses.
Bonifazi, Paolo ; Difato, Francesco ; Massobrio, Paolo ; Breschi, Gian L ; Pasquale, Valentina ; Levi, Timothée ; Goldin, Miri ; Bornat, Yannick ; Tedesco, Mariateresa ; Bisio, Marta ; Kanner, Sivan ; Galron, Ronit ; Tessadori, Jacopo ; Taverna, Stefano ; Chiappalone, Michela
Dans : Front Neural Circuits
https://hal.archives-ouvertes.fr/hal-00956625

In-vitro exposure of neuronal networks to the GSM-1800 signal.
Moretti, Daniela ; Garenne, André ; Haro, Emmanuelle ; Poulletier De Gannes, Florence ; Lagroye, Isabelle ; Lévêque, Philippe ; Veyret, Bernard ; Lewis, Noëlle
Dans : Bioelectromagnetics
https://hal.archives-ouvertes.fr/hal-00858399

In-vitro Exposure of Neuronal Networks to a GSM-1800 Signal
Moretti, Daniela ; Garenne, André ; Haro, Emmanuelle ; Poulletier De Gannes, F. ; Lagroye, Isabelle ; Lévêque, Philippe ; Veyret, Bernard ; Lewis, Noëlle
Dans : Bioelectromagnetics
https://hal.archives-ouvertes.fr/hal-00828018

Low-Gain, Low-Noise Integrated Neuronal Amplifier for Implantable Artifact-Reduction Recording System
Zbrzeski, Adeline ; Lewis, Noëlle ; Rummens, Francois ; Jung, Ranu ; N'Kaoua, Gilles ; Benazzouz, Abdelhamid ; Renaud, S.
Dans : J. Low Power Electron. Appl.
https://hal.archives-ouvertes.fr/hal-00986300

2012


Design of a Bioelectronics Hybrid System in Real Time and in Closed Loop
Bontorin, Guilherme ; Garenne, André ; Lopez, Colin ; Le Masson, Gwendal ; Renaud, Sylvie
Dans : Electronics
https://hal.inria.fr/hal-00828011

Application of IP-based Analog Platforms in the design of Neuromimetic Integrated Circuits
Levi, Timothée ; Lewis, Noëlle ; Tomas, Jean ; Renaud, Sylvie
Dans : IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
https://hal.archives-ouvertes.fr/hal-00765898

P169 Biocapteur hybride destiné au suivi fonctionnel à long terme et au criblage sur les îlots de Langerhans
Raoux, M. ; Bornat, Y. ; Quotb, A. ; Catargi, B. ; Renaud, S. ; Lang, J.
Dans : Journal of Diabetes & Metabolism
https://hal.archives-ouvertes.fr/hal-01648718

2011


Automated Parameter Estimation of the Hodgkin-Huxley Model Using the Differential Evolution Algorithm: Application to Neuromimetic Analog Integrated Circuits
Buhry, Laure ; Grassia, Filippo ; Giremus, Audrey ; Grivel, Eric ; Renaud, Sylvie ; Saïghi, Sylvain
Dans : Neural Computation
https://hal.archives-ouvertes.fr/hal-00625448

Neuromorphic silicon neuron circuits
Indiveri, Giacomo ; Linares-Barranco, Bernabé ; Julia Hamilton, Tara ; Van Schaik, André ; Etienne-Cummings, Ralph ; Delbruck, Tobi ; Liu, Shih-Chii ; Dudek, Piotr ; Häfliger, Philipp ; Renaud, Sylvie ; Schemmel, Johannes ; Cauwenberghs, Gert ; Arthur, John ; Hynna, Kai ; Folowosele, Fopefolu ; Saighi, Sylvain ; Serrano-Gotarredona, Teresa ; Wijekoon, Jayawan ; Wang, Yingxue ; Boahen, Kwabena
Dans : Frontiers in Neuroscience
https://hal.archives-ouvertes.fr/hal-00597675

Wavelet transform for real-time detection of action potentials in neural signals
Quotb, Adam ; Bornat, Yannick ; Renaud, Sylvie
Dans : Frontiers in neuroengineering
https://hal.archives-ouvertes.fr/hal-00609083

Non-invasive long-term and real-time analysis of endocrine cells on micro-electrode arrays
Raoux, Matthieu ; Bornat, Yannick ; Quotb, Adam ; Catargi, Bogdan ; Renaud, Sylvie ; Lang, Jochen
Dans : Journal of Physiology
https://hal.archives-ouvertes.fr/hal-00742984

A Library of Analog Operators Based on the Hodgkin-Huxley Formalism for the Design of Tunable, Real-Time, Silicon Neurons
Saïghi, Sylvain ; Bornat, Yannick ; Tomas, Jean ; Le Masson, Gwendal ; Renaud, Sylvie
Dans : IEEE Transactions on Biomedical Circuits and Systems
https://hal.archives-ouvertes.fr/hal-00562021

2010


Real-Time Simulation of Biologically Realistic Stochastic Neurons in VLSI
Chen, Hsin ; Saïghi, Sylvain ; Buhry, Laure ; Renaud, Sylvie
Dans : IEEE Transactions on Neural Networks
https://hal.archives-ouvertes.fr/hal-00551652

PAX: A mixed hardware/software simulation platform for spiking neural networks.
Renaud, S ; Tomas, J ; Lewis, N ; Bornat, Y ; Daouzli, A ; Rudolph, Michelle ; Destexhe, Alain ; Saïghi, S
Dans : Neural networks : the official journal of the International Neural Network Society
https://hal.archives-ouvertes.fr/hal-01179647

PAX: A mixed hardware/software simulation platform for spiking neural networks
Renaud, Sylvie ; Tomas, Jean ; Lewis, N. ; Bornat, Yannick ; Daouzli, A. ; Rudolph, Michelle ; Destexhe, Alain ; Saïghi, Sylvain
Dans : Neural Networks
https://hal.archives-ouvertes.fr/hal-00505024

2009


A CMOS Resizing Methodology for Analog Circuits: linear and non-linear applications
Levi, Timothée ; Tomas, Jean ; Lewis, Noëlle ; Fouillat, Pascal
Dans : IEEE Design & Test
https://hal.archives-ouvertes.fr/hal-00359990

A distance measurement platform dedicated to Electrical Engineering
Lewis, N. ; Billaud, M. ; Geoffroy, D. ; Cazenave, P. ; Zimmer, T.
Dans : IEEE Transactions on Learning Technologies
https://hal.archives-ouvertes.fr/hal-00450208

Developmental constraints revealed by co-variation within and among molar rows in two murine rodents.
Renaud, Sabrina ; Pantalacci, Sophie ; Quéré, Jean-Pierre ; Laudet, Vincent ; Auffray, Jean-Christophe
Dans : Evolution & Development
https://hal.archives-ouvertes.fr/halsde-00433314

2008


Large-Scale, High-Resolution Data Acquisition System for Extracellular Recording of Electrophysiological Activity
Imfeld, K. ; Neukom, S. ; Maccione, A. ; Bornat, Y. ; Martinoia, S. ; Farine, P.-A. ; Koudelka-Hep, M. ; Berdondini, L.
Dans : IEEE Transactions on Biomedical Engineering
https://hal.archives-ouvertes.fr/hal-00319351

2007


IP-based design for analogue ASICs: A case study
Levi, Timothée ; Lewis, N. ; Tomas, J. ; Fouillat, P.
Dans : Design&Reuse Articles
https://hal.archives-ouvertes.fr/hal-00522419

2006


Real-time simulations of networks of Hodgkin–Huxley neurons using analog circuits
Zou, Quan ; Bornat, Yannick ; Tomas, Jean ; Renaud, Sylvie ; Destexhe, Alain
Dans : Neurocomputing / EEG Neurocomputing
https://hal.archives-ouvertes.fr/hal-00182181

Analog-digital simulations of full conductance-based networks of spiking neurons with spike timing dependent plasticity.
Zou, Quan ; Bornat, Yannick ; Saïghi, Sylvain ; Tomas, Jean ; Renaud, Sylvie ; Destexhe, Alain
Dans : Network
https://hal.archives-ouvertes.fr/hal-00120641

2004


Hardware computation of conductance-based neuron models.
Alvado, L. ; Tomas, Jean ; Saighi, Sylvain ; Renaud, Sylvie ; Bal, Thierry ; Destexhe, Alain ; Le Masson, Gwendal
Dans : Neurocomputing
https://hal.archives-ouvertes.fr/hal-00018608

A neural simulation system based on biologically-realistic electronic neurons
Renaud, Sylvie ; Le Masson, Gwendal ; Alvado, Ludovic ; Saighi, Sylvain ; Tomas, Jean
Dans : Information Sciences
https://hal.archives-ouvertes.fr/hal-00203931

2002


VHDL-AMS Model of a Synchronous Oscillator including Phase Noise
Fakhfakh, Ahmed ; Lewis, Noëlle ; Begueret, Jean-Baptiste ; Levi, Herve
Dans : System on Chip Design Languages: Extended Papers: Best of Fdl'01 and Hdlcon'01, Kluver Academic Publishers
https://hal.archives-ouvertes.fr/hal-00183167

Contribution to ageing simulation of complex analogue circuit using VHDL-AMS behavioural modelling language
Mongellaz, Benoit ; Marc, François ; Lewis, Noëlle ; Danto, Yves
Dans : Microelectronics Reliability
https://hal.archives-ouvertes.fr/hal-00181804

1998


Method for BJT transit time evaluation
Zimmer, T. ; Duluc, J.B. ; Lewis, N.
Dans : Electronics Letters
https://hal.archives-ouvertes.fr/hal-01721403
Articles dans des revues sans comité de lecture → 2 Voir

2014


Biosensors in Diabetes : how to get the most out of evolution and transpose it into a signal
Renaud, Sylvie ; Catargi, Bogdan ; Lang, Jochen
Dans : IEEE pulse
https://hal.archives-ouvertes.fr/hal-00993190

2007


IP-based design for analogue ASICs: A case study
Levi, Timothée ; Lewis, Noëlle ; Tomas, Jean ; Fouillat, Pascal
Dans : Einfochips Dashboard
https://hal.archives-ouvertes.fr/hal-00522423
Communications avec actes (nationales) → 27 Voir

2014


Study of fibrosis induced by an implanted medical device
Lewis, Noëlle ; Renaud, Sylvie ; Lagroye, Isabelle ; ERIC, Mcadams ; BOGONEZ-FRANCO, P ; Noury, Norbert ; SOULIER, Fabien ; Bernard, Serge ; LETHIAS, C ; LAHUEC, Cyril ; Arzel, Matthieu ; AGNIEL, R ; KELLOUCHE, S ; BOISSIERE, M ; Carreiras, Franck ; PAUTHE, Emmanuel ; Bonneau, M ; Kang, Chantal ; Binczak, Stéphane ; PINNA, Andréa ; Granado, Bertrand ; Garda, Patrick ; TEROSIET, M ; GOGUIN, A ; HISTACE, A ; Romain, Olivier
Dans : Handicap, Paris (France)
https://hal.archives-ouvertes.fr/hal-01060241

2007


IP-Based Library for Analog Design Reuse
Levi, Timothée ; Lewis, N. ; Tomas, J. ; Fouillat, P.
Dans : GDR SoC-SIP, Paris (France)
https://hal.archives-ouvertes.fr/hal-00181424

IP-based design reuse for analogue systems: a case study
Levi, Timothée ; Tomas, J. ; Lewis, N. ; Fouillat, P.
Dans : Proceedings SPIE VLSI Circuits and Systems III, Maspalomas, Gran Canaria (Spain)
https://hal.archives-ouvertes.fr/hal-00181417

Spiking neural networks "in silico": from single neurons to large scale networks
Lewis, N. ; Renaud, S.
Dans : SSD 2007, Hammamet (Tunisia)
https://hal.archives-ouvertes.fr/hal-00181415

2006


PAX : un outil logiciel / matériel d'investigation pour les neurosciences computationnelles
Lewis, N. ; Bornat, Y. ; Alvado, L. ; Lopez, C. ; Daouzli, A. ; Levi, Timothée ; Tomas, J. ; Saighi, S. ; Renaud, S.
Dans : NeuroComp, 1ère conférence française de Neurosciences Computationnelles, Pont-à-Mousson (France)
https://hal.archives-ouvertes.fr/hal-00181386

Design of a modular and mixed neuromimetic ASIC
Tomas, J. ; Bornat, Y. ; Saighi, S. ; Levi, Timothée ; Renaud, S.
Dans : ICECS 2006, 13th IEEE International Conference on Electronics, Circuits and Systems, (France)
https://hal.archives-ouvertes.fr/hal-00181404

2005


BiCMOS Analog Integrated Circuits for Embedded Spiking Neural Networks
Bornat, Yannick ; Tomas, Jean ; Saighi, Sylvain ; Renaud, Sylvie
Dans : XX Conference on Design of Circuits and Integrated Systems, DCIS 2005, Lisboa (Portugal)
https://hal.archives-ouvertes.fr/hal-00203934

A Neuromimetic Integrated Circuit for Interactive Real-Time Simulation
Saighi, Sylvain ; Tomas, Jean ; Bornat, Yannick ; Renaud, Sylvie
Dans : 1st International Work-Conference on the Interplay Between Natural and Artificial Computation, IWINAC 2005, Las Palmas (Spain)
https://hal.archives-ouvertes.fr/hal-00203933

A Conductance-Based Silicon Neuron with Dynamically Tunable Model Parameters
Saighi, Sylvain ; Tomas, Jean ; Bornat, Yannick ; Renaud, Sylvie
Dans : 2nd International IEEE EMBS Conference on Neural Engineering, Arlington (United States)
https://hal.archives-ouvertes.fr/hal-00203932

2004


A Mixed Neuromorphic ASIC for Computional Neurosciences
Saighi, Sylvain ; Tomas, Jean ; Bornat, Yannick ; Renaud, Sylvie
Dans : XIX Conference on Design of Circuits and Integrated Systems, DCIS 2004, (France)
https://hal.archives-ouvertes.fr/hal-00203935

2003


Hardware computation of conductance-based neuron models
Alvado, Ludovic ; Tomas, Jean ; Saighi, Sylvain ; Renaud, Sylvie ; Bal, T. ; Destexhe, A. ; Le Masson, Gwendal
Dans : Twelfth Annual Computational Neuroscience Meeting, CNS 2003, (Spain)
https://hal.archives-ouvertes.fr/hal-00203937

An Exponential-Decay Synapse Integrated Circuit for Bio-inspired Neural Networks
Alvado, Ludovic ; Saighi, Sylvain ; Tomas, Jean ; Renaud, Sylvie
Dans : 7th International Work-Conference on Artificial and Natural Networks, IWANN'2003, (Spain)
https://hal.archives-ouvertes.fr/hal-00203936

Modèle Comportemental VHDL-AMS d'un Amplificateur CMOS à Transconductance: Application à la conception de filtres
Mongellaz, Benoit ; Schmitt, A. ; Lewis, Noëlle ; Marc, François ; Danto, Yves
Dans : SETIT 2003, (Tunisia)
https://hal.archives-ouvertes.fr/hal-00181901

Modelling of transient noise sources with VHDL-AMS and normative spectral interpretation
Monnerie, Guillaume ; Lewis, Noëlle ; Dallet, Dominique ; Levi, Herve ; Robbe, Michel
Dans : Forum on Design Languages, FDL'03, (Germany)
https://hal.archives-ouvertes.fr/hal-00183670

Silicon Integration of Biological Neurons Models
Saighi, Sylvain ; Tomas, Jean ; Alvado, Ludovic ; Bornat, Yannick ; Renaud, Sylvie
Dans : XVIII Conference on Design of Circuits and Integrated Systems, DCIS 2003, (Spain)
https://hal.archives-ouvertes.fr/hal-00203938

2002


Behavioural modelling of phase noise and jitter in Voltage-Controlled Oscillators with VHDL-AMS
Fakhfakh, Ahmed ; Lewis, Noëlle ; Tomas, Jean ; Levi, Herve
Dans : 1st IEEE International Conference on Circuits and Systems for Communication, ICCSC02, (Russia)
https://hal.archives-ouvertes.fr/hal-00203952

Simulateur VLSI analogique de neurones biologiquement réalistes
Renaud, Sylvie ; Saighi, Sylvain ; Alvado, Ludovic ; Tomas, Jean ; Le Masson, Gwendal ; Bal, T.
Dans : NSI'2002, (France)
https://hal.archives-ouvertes.fr/hal-00203940

2001


Neurones artificiels sur ASIC en utilisant les propriétés du transistor MOS en régime de faible inversion
Alvado, Ludovic ; Tomas, Jean ; Renaud, Sylvie
Dans : TAISA'2001, (France)
https://hal.archives-ouvertes.fr/hal-00203954

Design of an Analogue ASIC using subthreshold CMOS transistors to model biological neurons
Alvado, Ludovic ; Tomas, Jean ; Renaud, Sylvie ; Douence, Vincent
Dans : CICC'2001, (United States)
https://hal.archives-ouvertes.fr/hal-00203953

VHDL-AMS for mixed technology and mixed signal, an overview
Charlot, Jean Jacques ; Lewis, Noëlle ; Zimmer, Thomas ; Levi, Herve
Dans : 9th Mediterranean Conference on Control and Automation, MED 01, (Croatia)
https://hal.archives-ouvertes.fr/hal-00203975

A field-programmable conductance array IC for biological neurons modeling
Douence, Vincent ; Renaud, Sylvie ; Saighi, Sylvain ; Le Masson, Gwendal
Dans : 6th International Work-Conference on Artificial and Natural Neural Networks, IWANN'2001, (Spain)
https://hal.archives-ouvertes.fr/hal-00203941

Study and behavioral simulation of phase noise and jitter in oscillators
Fakhfakh, Ahmed ; Lewis, Noëlle ; Deval, Yann ; Levi, Herve
Dans : 2001 IEEE International Symposium on Circuits and Systems, ISCAS 2001, (Australia)
https://hal.archives-ouvertes.fr/hal-00184304

2000


Speaking VHDL-AMS, a Newly Standarized Description Language, for Teaching Mixed Technology and Mixed Signal Systems
Charlot, Jean Jacques ; Oudinot, Jean ; Lewis, Noëlle ; Zimmer, Thomas ; Levi, Herve
Dans : International Conference on Information Technology Based Higher Education and Training, ITHET 2000, (Turkey)
https://hal.archives-ouvertes.fr/hal-00203977

A Systematic Approach for the Behavioural Modelling of Analogue Integrated Systems
Fakhfakh, Ahmed ; Lewis, Noëlle ; Levi, Herve ; Zimmer, Thomas
Dans : International Conference on Artificial and Computational Intelligence For Decision, Control and Automation In Engineering and Industrial Applications, ACIDCA 2000, (Tunisia)
https://hal.archives-ouvertes.fr/hal-00203976

1999


Using VHDL-AMS to build a specific analogue behavioural model library
Lewis, Noëlle ; Charlot, Jean Jacques ; Levi, Herve ; Zimmer, Thomas ; Laflaquiere, Arnaud
Dans : International Forum on Design Languages, FDL 99, (France)
https://hal.archives-ouvertes.fr/hal-00203980

Comparing four analog HDL modelings and simulations of a complex system
Lewis, Noëlle ; Charlot, Jean Jacques ; Zimmer, Thomas ; Levi, Herve ; Laflaquiere, Arnaud
Dans : IEEE/ACM International Workshop on Behavioral Modeling And Simulation, BMAS 99, (United States)
https://hal.archives-ouvertes.fr/hal-00203978

Hierarchical Analogue Design and Behavioral Modelling
Zimmer, Thomas ; Lewis, Noëlle ; Fakhfakh, Ahmed ; Ardouin, Bertrand ; Levi, Herve ; Fouillat, Pascal
Dans : Microelectronic Systems Education Conference, MSE99, (United States)
https://hal.archives-ouvertes.fr/hal-00203979
Communications avec actes (internationales) → 56 Voir

2016


Stimulation strategies for neurons and fibres Connecting biological and artificial neural networks
Buccelli, Stefano ; Tessadori, Jacopo ; Bornat, Yannick ; Pasquale, Valentina ; Ambroise, Matthieu ; Levi, Timothée ; Massobrio, Paolo ; Chiappalone, Michela
Dans : 10th International Meeting on Substrate-Integrated Microelectrode Arrays (MEA 2016), Reutlingen (Germany)
https://hal.archives-ouvertes.fr/hal-01567554

2015


Relevance of impedance spectroscopy for the monitoring of implant-induced fibrosis: A preliminary study
Lewis, Noëlle ; Lahuec, C ; Renaud, S ; Mcadams, E ; BOGONEZ-FRANCO, P ; LETHIAS, C ; KELLOUCHE, S ; Carreiras, F ; Pinna, A ; Histace, Aymeric ; BOISSIERE, M ; Pauthe, E ; Lagroye, I ; SOULIER, Fabien ; Bernard, Serge ; Binczak, S ; Granado, Bertrand ; Garda, Patrick ; TEROSIET, M ; Goguin, Alexandre ; Romain, Olivier
Dans : BIOCAS: Biomedical Circuits and Systems, Atlanta (United States)
https://hal.archives-ouvertes.fr/hal-01246840

CMOS differential neural amplifier with high input impedance
Rummens, Francois ; Renaud, Sylvie ; Lewis, Noelle
Dans : 2015 IEEE 13th International New Circuits and Systems Conference (NEWCAS), Grenoble (France)
https://hal.archives-ouvertes.fr/hal-01467331

A versatile fast-development platform applied to closed-loop diaphragmatic pacing
Zbrzeski, Adeline ; Siu, Ricardo ; Bornat, Yannick ; Hillen, Brian ; Jung, Ranu ; Renaud, Sylvie
Dans : 7th International IEEE/EMBS Conference on Neural Engineering (NER), Montpellier (France)
https://hal.archives-ouvertes.fr/hal-01347976

2014


Biorealistic Spiking Neural Network on FPGA
Ambroise, Matthieu ; Levi, Timothée ; Bornat, Yannick ; Saighi, Sylvain
Dans : Information Sciences and Systems (CISS), 2013 47th Annual Conference on, Baltimore (United States)
https://hal.archives-ouvertes.fr/hal-00956630

Silicon neuron dedicated to memristive spiking neural networks
Lecerf, Gwendal ; Tomas, Jean ; Boyn, Sören ; Girod, Stéphanie ; Mangalore, Ashwin ; Grollier, Julie ; Saïghi, Sylvain
Dans : Circuits and Systems (ISCAS), 2014 IEEE International Symposium on, Melbourne (Australia)
https://hal.archives-ouvertes.fr/hal-01093162

Biomimetic neural networks for hybrid experiments
Levi, Timothée ; Ambroise, Matthieu ; Grassia, Filippo ; Malot, Olivia ; Saighi, Sylvain ; Bornat, Yannick ; Tomas, Jean ; Renaud, Sylvie
Dans : International Symposium on Neuromorphic and Non-linear Engineering, ISNNE, Tokyo (Japan)
https://hal.archives-ouvertes.fr/hal-01227638

2013


In vitro experimental and theoretical studies to restore lost neuronal functions: the Brain Bow experimental framework
Bonifazi, Paolo ; Massobrio, Paolo ; Levi, Timothée ; Difato, Francesco ; Breschi, Gian L ; Pasquale, V. ; Goldin, Miri ; Ambroise, Matthieu ; Bornat, Yannick ; Tedesco, Mariateresa ; Bisio, Marta ; Frega, Marta ; Tessadori, Jacopo ; Nowak, P. ; Grassia, Filippo ; Kanner, Sivan ; Ronit, G. ; Renaud, Sylvie ; Martinoia, Sergio ; Taverna, Stefano ; Chiappalone, Michela
Dans : 6th International IEEE EMBS Conference on Neural Engineering, (United States)
https://hal.archives-ouvertes.fr/hal-00966013

Challenges in recording and stimulation of living neural network based on original micro-electrode array (MEA) developments
Cottance, Myline ; Nazeer, Sebastien ; Rousseau, L. ; Lissorgues, Gaelle ; Joucla, Sébastien ; Yvert, Blaise ; Lewis, Noëlle ; Bornat, Yannick ; Renaud, S.
Dans : 2013 IEEE 11th International Conference on New Circuits and Systems (NEWCAS), (France)
https://hal.archives-ouvertes.fr/hal-00980781

Generation of Locomotor-Like Activity in the Isolated Rat Spinal Cord by Electrical Microstimulations Driven by an Artificial CPG
Joucla, Sébastien ; Ambroise, Matthieu ; Levi, Timothée ; Lafon, Thierry ; Chauvet, P. ; Rousseau, L. ; Lissorgues, Gaelle ; Saïghi, Sylvain ; Bornat, Yannick ; Lewis, Noëlle ; Renaud, Sylvie ; Yvert, Blaise
Dans : 6th International IEEE EMBS Conference on Neural Engineering, (United States)
https://hal.archives-ouvertes.fr/hal-00966012

Characterization of a non linear fractional model of electrode-tissue impedance for neuronal stimulation
Kolbl, FLorian ; Sabatier, Jocelyn ; N'Kaoua, Gilles ; Naudet, Frédéric ; Faggiani, Emilie ; Benazzouz, Abdelhamid ; Renaud, Sylvie ; Lewis, Noëlle
Dans : Biomedical Circuits and Systems Conference (BioCAS), 2013 IEEE, Rotterdam (Netherlands)
https://hal.archives-ouvertes.fr/hal-00986311

A novel bioelectronic glucose sensor to process distinct electrical activities of pancreatic beta-cells
Nguyen, Quang Vinh ; Caro, Anton ; Raoux, Matthieu ; Quotb, Adam ; Floderer, Jean-Baptiste ; Bornat, Yannick ; Renaud, Sylvie ; Lang, Jochen
Dans : 35th Annual International Conference of the IEEE EMBS, (Japan)
https://hal.archives-ouvertes.fr/hal-00980774

2012


Linking biological and artificial neuronal assemblies to restore lost brain functions
Chiappalone, Michela ; Difato, Francesco ; Breschi, Gian L ; Bisio, Marta ; Pasquale, Valentina ; Bornat, Yannick ; Massobrio, Paolo ; Levi, Timothée ; Taverna, Stefano ; Bonifazi, Paolo
Dans : Neuroscience 2012, the Society for Neuroscience 42nd Annual Meeting, (United States)
https://hal.archives-ouvertes.fr/hal-00966015

The ERNAM project: exposure of neuronal networks to the GSM-1800 signal
Moretti, Daniela ; Garenne, André ; Lewis, Noëlle ; Poulletier De Gannes, Florence ; Haro, Emmanuelle ; Lagroye, Isabelle ; Bornat, Yannick ; Boutaib, Youssef ; Renaud, Sylvie ; Veyret, Bernard
Dans : BEMS 2012 - 34th Annual Meeting of the Bioelectromagnetics Society, Brisbane (Australia)
https://hal.inria.fr/hal-00828014

NeuroBetaMed: A re-configurable wavelet-based event detection circuit for in vitro biological signals
Quotb, Adam ; Bornat, Yannick ; Raoux, Matthieu ; Lang, Jochen ; Renaud, Sylvie
Dans : Circuits and Systems (ISCAS), 2012 IEEE International Symposium on, Seoul (South Korea)
https://hal.archives-ouvertes.fr/hal-00742324

2011


A Neuromimetic Spiking Neural Network for Simulating Cortical Circuits
Grassia, Filippo ; Levi, Timothée ; Tomas, Jean ; Renaud, Sylvie ; Saïghi, Sylvain
Dans : 45th Annual Conference on Information Sciences ans Systems, Baltimore (United States)
https://hal.archives-ouvertes.fr/hal-00597648

The ERNAM project: exposure of neuronal networks to the GSM-1800 signal
Moretti, Daniela ; Lewis, Noëlle ; Garenne, André ; Poulletier De Gannes, Florence ; Haro, Emmanuelle ; Lagroye, Isabelle ; Bornat, Yannick ; Boutaib, Youssef ; Saighi, Sylvain ; Renaud, Sylvie ; Veyret, Bernard
Dans : BEMS 33rd Annual Meeting, Halifax (Canada)
https://hal.archives-ouvertes.fr/hal-00585678

A Tunable Integrated Device for LFP Tracking
Zbrzeski, Adeline ; Lewis, Noëlle ; Syed, Emilie ; Benazzouz, Abdelhamid ; Boraud, Thomas ; Renaud, Sylvie
Dans : 26th Conference on Design of Circuits and Integrated systems (DCIS 2011), Albufeira (Portugal)
https://hal.archives-ouvertes.fr/hal-00667617

2010


Guaranteeing Spike Arrival Time in Multiboard & Multichip Spiking Neural Networks
Belhadj, Bilel ; Tomas, Jean ; Malot, Olivia ; Bornat, Yannick ; N'Kaoua, Gilles ; Renaud, Sylvie
Dans : ISCAS 2010, Paris (France)
https://hal.archives-ouvertes.fr/hal-00504025

Detection of electrical activity of pancreatic beta-cells using micro-electrode arrays
Bornat, Yannick ; Raoux, M. ; Boutaïb, Youssef ; Morin, F. ; Charpentier, G. ; Lang, J. ; Renaud, Sylvie
Dans : DELTA 2010, Ho Chi Minh City (Vietnam)
https://hal.archives-ouvertes.fr/hal-00501820

Efficient phase noise modeling of a PLL-based frequency synthesizer
Eynard, Goulven ; Lewis, Noëlle ; Dallet, Dominique ; Le Gal, Bertrand
Dans : 4th International Symposium on Communications, Control and Signal Processing (ISCCSP), (Cyprus)
https://hal.archives-ouvertes.fr/hal-00560326

In Vivo Electrical Characterization of Deep Brain Electrode and Impact on Bio-amplifier Design
Kölbl, Florian ; Zbrzeski, Adeline ; Syed, Emilie ; Renaud, Sylvie ; Lewis, Noëlle
Dans : IEEE Biocas 2010, Paphos (Cyprus)
https://hal.archives-ouvertes.fr/hal-00585051

Real-Time Multi-board Architecture for Analog Spiking Neural Networks
SaÏghi, S. ; Tomas, J. ; Bornat, Y. ; Belhadj, B. ; Malot, O. ; Renaud, S.
Dans : ISCAS 2010, Paris (France)
https://hal.archives-ouvertes.fr/hal-00505314

A conductance-based silicon neuron with membrane-voltage dependent temporal dynamics
Tomas, Jean ; Saïghi, Sylvain ; Renaud, Sylvie ; Silver, Jason ; Barnaby, Hugh
Dans : IEEE North East Workshop on Circuits and Systems, (Canada)
https://hal.archives-ouvertes.fr/hal-00982123

A conductance-based silicon neuron with membrane-voltage dependent temporal dynamics
Tomas, J. ; Silver, J. ; SaÏghi, S. ; Barnaby, H. ; Renaud, S.
Dans : IEEE North East Workshop on Circuits and Systems 2010 (NEWCAS 2010), Montréal (Canada)
https://hal.archives-ouvertes.fr/hal-00505310

A Programmable BioAmplifier on FPAA for in vivo Neural Recording
Zbrzeski, Adeline ; Hasler, Paul ; Kölbl, Florian ; Syed, Emilie ; Lewis, Noëlle ; Renaud, Sylvie
Dans : IEEE Biocas 2010, Paphos (Cyprus)
https://hal.archives-ouvertes.fr/hal-00585043

2009


Digital Mapping of a Realistic Spike Timing Plasticity Model for Real-time Neural Simulations
Belhadj, B. ; Tomas, J. ; Bornat, Y. ; Daouzli, A. ; Malot, O. ; Renaud, S.
Dans : Design of Circuits an Integrated Circuits Conference, Zaragoza (Spain)
https://hal.archives-ouvertes.fr/hal-00438274

Token-Passing Communication Protocol in Hardware based Real-time Spiking Neural Networks
Belhadj, B. ; Tomas, J. ; Malot, O. ; Bornat, Y. ; N'Kaoua, G. ; Renaud, S.
Dans : International Conference on Bioengineered and Bioinspired Systems, Dresden (Germany)
https://hal.archives-ouvertes.fr/hal-00414614

A real-time setup for multisite stimulation on living neural networks
Bontorin, G. ; Garenne, A. ; Tomas, J. ; Lopez, C. ; O. Morin, F. ; Renaud, S.
Dans : NEWCAS 09, Toulouse (France)
https://hal.archives-ouvertes.fr/hal-00402449

Automated Tuning of Analog Neuromimetic Integrated Circuits
Buhry, L. ; SaÏghi, S. ; Giremus, A. ; Grivel, E. ; Renaud, S.
Dans : Conference on Biomedical Circuits and Systems, Beijing (China)
https://hal.archives-ouvertes.fr/hal-00438269

New variants of the Differential Evolution algorithm: application for neuroscientists
Buhry, Laure ; Giremus, Audrey ; Grivel, Eric ; Saïghi, Sylvain ; Renaud, S.
Dans : European Signal Processing conference, EUSIPCO, Glasgow (United Kingdom)
https://hal.archives-ouvertes.fr/hal-00400824

Convergence in an Adaptive Neural Network: The Influence of Noise Inputs Correlation
Daouzli, A. ; SaÏghi, S. ; Rudolph, M. ; Destexhe, A. ; Renaud, S.
Dans : International Work-Conference on Artificial Neural Networks (IWANN'09), Salamanca (Spain)
https://hal.archives-ouvertes.fr/hal-00396825

Low-Power Linear-Phase Delay Filters for Neural Signal Processing: Comparison and Synthesis
Gosselin, Benoit ; Zbrzeski, A. ; Sawan, M. ; Kerhervé, Eric
Dans : 2009 IEEE Int. Symposium on Circuits and Systems (ISCAS), Taipei (Taiwan)
https://hal.archives-ouvertes.fr/hal-00401356

2008


FPGA-based Architecture for Real-time Synaptic Plasticity Computation
Belhadj, B. ; Tomas, J. ; Malot, O. ; N'Kaoua, G. ; Bornat, Y. ; Renaud, S.
Dans : International Conference on Electronics, Circuits and Systems, (ICECS'08), Malte (Malta)
https://hal.archives-ouvertes.fr/hal-00320751

A Real-time Setup for Multisite Signal Recording and Processing in Living Neural Networks
Bontorin, G. ; Lopez, C. ; Bornat, Y. ; Lewis, N. ; Renaud, S. ; Garenne, A. ; Chanaud, M. ; Le Masson, G.
Dans : InternationaI Symposium on Circuits And Systems 2008 (ISCAS08), Seattle (United States)
https://hal.archives-ouvertes.fr/hal-00288433

Parameter estimation of the Hodgkin-Huxley model using metaheuristics: application to neuromimetic analog integrated circuits
Buhry, Laure ; Saïghi, Sylvain ; Giremus, Audrey ; Grivel, Eric ; Renaud, Sylvie
Dans : Biomedical Circuits and Systems Conference (BIOCAS), Baltimore (United States)
https://hal.archives-ouvertes.fr/hal-00347187

Weights Convergence and Spikes Correlation in an Adaptive Neural Network Implemented on VLSI
Daouzli, Adel ; Saïghi, Sylvain ; Buhry, Laure ; Bornat, Yannick ; Renaud, Sylvie
Dans : Bio-inspired Systems and Signal Processing (BIOSIGNALS), (France)
https://hal.archives-ouvertes.fr/hal-00288431

IP-based methodology for analog design flow: Application on neuromorphic engineering
Levi, Timothée ; Lewis, N. ; Tomas, J. ; Fouillat, P.
Dans : IEEE NEWSCAS-TAISA 2008, Montréal (Canada)
https://hal.archives-ouvertes.fr/hal-00514205

An E-Learning Experience in Practical Electronics: Technological and Pedagogical Aspects
Lewis, Noelle ; Zimmer, Thomas ; Billaud, Michel ; Geoffroy, Didier
Dans : 5th Congress of Scientific Research Outlook in the Arab World, Fez (Morocco)
https://hal.archives-ouvertes.fr/hal-00327562

Electronic Practical Course via the Web in a Virtual Laboratory
Mnif, Hassene ; Sahnoun, Salwa ; Hdiji, Fatma ; Geoffroy, Didier ; Billaud, Michel ; Lewis, Noelle ; Zimmer, Thomas
Dans : Conference REV 2008, Düsseldorf (Germany)
https://hal.archives-ouvertes.fr/hal-00327567

Adjusting the Neurons Models in Neuromimetic ICs using the Voltage-Clamp Technique
SaÏghi, S. ; Buhry, L. ; Bornat, Y. ; N'Kaoua, G. ; Tomas, J. ; Renaud, S.
Dans : InternationaI Symposium on Circuits And Systems 2008 (ISCAS08), Seattle (United States)
https://hal.archives-ouvertes.fr/hal-00288432

2007


Low noise and low Cost Neural Amplifiers
Bontorin, Guilherme ; Tomas, Jean ; Renaud, Sylvie
Dans : Int. Conf. on Electronics, Circuits and Systems (ICECS'2007),, Marrakech (Morocco)
https://hal.archives-ouvertes.fr/hal-00288402

A Real-Time Closed-Loop Setup for Hybrid Neural Networks
Bontorin, G. ; Renaud, S. ; Garenne, A. ; Alvado, L. ; Le Masson, G. ; Tomas, J.
Dans : Proc. of the 29th Annaul Int. Conference of the IEEE EMBS, Lyon (France)
https://hal.archives-ouvertes.fr/hal-00181426

Design of Analog/Digital Simulator Dedicated to Real-time Neurocomputing
Bornat, Y. ; Tomas, J. ; Lopez, C. ; Malot, O. ; Belhadj, B. ; Renaud, S.
Dans : DCIS 2007, Sevilla (Spain)
https://hal.archives-ouvertes.fr/hal-00404133

An IP-based library for the design of analog Hodgkin Huxley neurons
Levi, Timothée ; Lewis, N. ; Bornat, Yannick ; Destexhe, Alain ; Tomas, Jean
Dans : Systems, Signal and Devices Conference SSD 2007, Hammamet (Tunisia)
https://hal.archives-ouvertes.fr/hal-00514214

Scaling Guidelines for CMOS Linear Analog Design
Levi, Timothée ; Lewis, N. ; Tomas, J. ; Fouillat, P.
Dans : International Conference on Ph.D. Research in Microelectronics & Electronics, Bordeaux (France)
https://hal.archives-ouvertes.fr/hal-00414788

Resizing methodology for CMOS analog circuit
Levi, Timothée ; Tomas, J. ; Lewis, N. ; Fouillat, P.
Dans : Proceedings SPIE VLSI Circuits and Systems III, Maspalomas, Gran Canaria (Spain)
https://hal.archives-ouvertes.fr/hal-00181420

An IP-based library for the design of analog Hodgkin Huxley neurons
Levi, Timothée ; Lewis, N. ; Bornat, Y. ; Destexhe, A. ; Tomas, J.
Dans : SSD 2007, Hammamet (Tunisia)
https://hal.archives-ouvertes.fr/hal-00181412

Neuromimetic ICs with analog cores: an alternative for simulating spiking neural networks
Renaud, Sylvie ; Tomas, Jean ; Bornat, Yannick ; Daouzli, Adel ; Saïghi, Sylvain
Dans : ISCAS'07, New-Orleans (United States)
https://hal.archives-ouvertes.fr/hal-00161313

A first step towards in silico neuronal implementation of early-vision map
Rochel, O. ; Chemla, S. ; Kornprobst, Pierre ; Vieville, Thierry ; Daouzli, A. ; Saighi, S. ; Lopez, C. ; Renaud, S.
Dans : Systems, Signal and Devices Conference SSD 2007, Hammamet (Tunisia)
https://hal.archives-ouvertes.fr/hal-00181413

2006


An Analog/Digital Simulation System for Biomimetic Neural Networks
Bornat, Y. ; Renaud, S. ; Tomas, J. ; Saighi, S. ; Zou, Q. ; Destexhe, A.
Dans : EPFL Latsis Symposium 2006, Lausanne (Switzerland)
https://hal.archives-ouvertes.fr/hal-00181384

IP-based design for analogue ASICs: A case study
Levi, Timothée ; Lewis, N. ; Tomas, J. ; Fouillat, P.
Dans : IP-based SoC Design Conference 2006, IP-SoC 2006, Grenoble (France)
https://hal.archives-ouvertes.fr/hal-00181401

Scaling Rules for MOS Analog Design Reuse
Levi, Timothée ; Lewis, N. ; Tomas, J. ; Fouillat, P.
Dans : Mixed Design of Integrated Circuits and Systems MIXDES 2006, Gdynia (Poland)
https://hal.archives-ouvertes.fr/hal-00181379

Neuromimetic ICs and System for Parameters Extraction in Biological Neuron Models
Saighi, S. ; Bornat, Y. ; Tomas, J. ; Renaud, S.
Dans : InternationaI Symposium on Circuits And Systems 2006, ISCAS06, sland of Kos (Greece)
https://hal.archives-ouvertes.fr/hal-00181370

2000


MEDICIS : a new Tool for Remote Programmable FPGA Circuit Testing
Nouel, Patrice ; Kadionik, Patrice ; Renaud, Sylvie
Dans : IMTC: IEEE Instrumentation and Measurement Technology Conference, Baltimore (United States)
https://hal.archives-ouvertes.fr/hal-00183033

1998


BJT avalanche breakdown voltage improvement by introduction of a floating P-layer in the epitaxial collector region
Zimmer, Thomas ; N?doye, M. ; Lewis, Noelle ; Batiste Duluc, Jean ; Fremont, Helene ; Paul Dom, Jean
Dans : Symposium on Microelectronic Facturing, Santa Clara (United States)
https://hal.archives-ouvertes.fr/hal-00189380
Communications sans actes → 21 Voir

2017


Biomimetic neural network for modifying biological dynamics during hybrid experiments
Ambroise, Matthieu ; Buccelli, Stefano ; Grassia, Filippo ; Pirog, Antoine ; Bornat, Yannick ; Chiappalone, Michela ; Levi, Timothée
Dans : 22th International Symposium on Artificial Life and Robotics, Beppu (Japan)
https://hal.archives-ouvertes.fr/hal-01567497

Restoring lost communication between in vitro neuronal assemblies
Buccelli, Stefano ; Tessadori, Jacopo ; Martines, Laura ; Bornat, Yannick ; Levi, Timothée ; Averna, Alberto ; Difato, Francesco ; Colombi, Ilaria ; Tedesco, Mariateresa ; Massobrio, Paolo ; Pasquale, Valentina ; Chiappalone, Michela
Dans : IEEE-NER conference, Shanghai (China)
https://hal.archives-ouvertes.fr/hal-01567498

An IC-Based Controllable Stimulator for Respiratory Muscle Stimulation Investigations
Castelli, Jonathan ; Kolbl, Florian ; Siu, Ricardo ; N'Kaoua, Gilles ; Bornat, Yannick ; Mangalore, Ashwin ; Hillen, Brian ; Abbas, James ; Renaud, Sylvie ; Ranu, Jung ; Lewis, Noëlle
Dans : IEEE EMBC, Jeju Island (South Korea)
https://hal.archives-ouvertes.fr/hal-01593374

MOdulaTion dU Signal RF et effets sur le cerveau : approche in vivo et in vitro
Lewis, Noëlle
Dans : Journée Scientifique ANSES Radiofréquences & santé, Paris (France)
https://hal.archives-ouvertes.fr/hal-01720429

A versatile electrode sorting module for MEAs: implementation in a FPGA-based real-time system
Pirog, Antoine ; Renaud, Sylvie ; Bornat, Yannick
Dans : IEEE Biomedical Circuits and Systems Conference (BioCAS), Turin (Italy)
https://hal.archives-ouvertes.fr/hal-01719658

2016


Circuits de stimulation et de surveillance de l’interface tissu/implant
Castelli, Jonathan ; Lewis, Noëlle ; Renaud, Sylvie
Dans : GDR SOC-SIP, Nantes (France)
https://hal.archives-ouvertes.fr/hal-01593397

Decrease in burst activity of neuronal networks under exposure to RF as a function of SAR for the CW and GSM-1800 signals
El Khoueiry, Corinne ; Camera, Francesca ; Orlacchio, Rosa ; Renom, Rémy ; Garenne, André ; Poulletier De Gannes, F. ; Poque-Haro, Emmanuelle ; Lagroye, I ; Bernard, Veyret ; Lewis, Noëlle
Dans : Annual Meeting of BioElectroMagnetics Society, BEMS, 2016, Ghent (Belgium)
https://hal.archives-ouvertes.fr/hal-01720428

Closing the Bioelectronic loop
Renaud, Sylvie
Dans : International Workshop on Bio-inspired Systems, Bioelectronics, and Machine Intelligence (BioPro 2016), HsinSHu (Taiwan)
https://hal.archives-ouvertes.fr/hal-01467332

Optimizing devices and processing at the bio-electronic interface
Renaud, Sylvie ; Bornat, Yannick ; Lewis, Noëlle
Dans : The IEEE MTT International Microwave Symposium (IMS) 2016, San Diego (United States)
https://hal.archives-ouvertes.fr/hal-01467309

2015


Resource Optimized Processor for Real-Time Neural Activity Monitoring
Bornat, Y. ; Quotb, Adam ; Lewis, Noëlle ; Renaud, Sylvie
Dans : VLSI (ISVLSI), 2015 IEEE Computer Society Annual Symposium on, Montpellier (France)
https://hal.archives-ouvertes.fr/hal-01648712

2014


Decreased electrical activity in neuronal networks exposed to CW and GSM-1800 signals
Moretti, D. ; Garenne, André ; Poulletier De Gannes, Florence ; Azzopardi, Stephane ; Roder, Raphaël ; Haro, Emmanuelle ; Lagroye, Isabelle ; Veyret, Bernard ; Lewis, Noëlle
Dans : BIOEM2014 conference, Cape Town (South Africa)
https://hal.archives-ouvertes.fr/hal-01016649

2013


Generation of Locomotor-Like Activity in the Isolated Rat Spinal Cord by Electrical Microstimulations Driven by an Artificial CPG
Joucla, Sébastien ; Ambroise, Matthieu ; Levi, Timothée ; Lafon, Thierry ; Chauvet, P. ; Rousseau, L. ; Lissorgues, Gaelle ; Saïghi, Sylvain ; Bornat, Yannick ; Lewis, Noëlle ; Renaud, Sylvie ; Yvert, Blaise
Dans : GDR multielectrode systems & signal processing for neuroscience, (France)
https://hal.archives-ouvertes.fr/hal-00966014

Activity of neuronal networks exposed to the GSM-1800 signal
Moretti, Daniela ; Garenne, André ; Poulletier De Gannes, F. ; Haro, Emmanuelle ; Lagroye, I ; Bernard, Veyret ; Lewis, Noëlle
Dans : Annual Meeting of BioElectroMagnetics Society, BEMS, 2013, Thessalonique (Greece)
https://hal.archives-ouvertes.fr/hal-01720407

2012


Analysis of the activity of neuronal networks exposed to the GSM-1800 signal
Moretti, D. ; Lewis, N. ; Garenne, A. ; Poulletier De Gannes, F. ; Haro, E. ; Lagroye, I. ; Veyret, B.
Dans : 34th Annual Meeting of the Bioelectromagnetics Society, Brisbane (Australia)
https://hal.archives-ouvertes.fr/hal-00718989

The ERNAM project: exposure of neuronal networks to the GSM-1800 signal
Moretti, D. ; Lewis, N. ; Garenne, A. ; Poulletier De Gannes, F. ; Haro, E. ; Lagroye, I. ; Bornat, Y. ; Boutaib, Y. ; Saighi, S. ; Renaud, S. ; Veyret, B.
Dans : Champs Electromagnétiques : De la Dosimétrie à la Santé Humaine. Journées Scientifiques. URSI France, Paris (France)
https://hal.archives-ouvertes.fr/hal-00718971

2008


Estimation des paramétres du modéle d'Hodgkin-Huxley par des métaheuristiques
Buhry, Laure ; Saighi, Sylvain ; Giremus, Audrey ; Grivel, Eric ; Renaud, Sylvie
Dans : Deuxième conférence française de Neurosciences Computationnelles, "Neurocomp08", Marseille (France)
https://hal.archives-ouvertes.fr/hal-00331588

2007


IP-Based Library for Analog Design Reuse
Levi, Timothée ; Lewis, N. ; Tomas, J. ; Fouillat, P.
Dans : GDR SoC-SIP, Paris (France)
https://hal.archives-ouvertes.fr/hal-00514216

2005


Real time simulations of networks of Hodgkin-Huxley neurons using analog circuits
Zou, Q. ; Bornat, Y. ; Tomas, J. ; Renaud, S. ; Destexhe, A.
Dans : Annual Computational Neuroscience Meeting, (CNS 2005), (United States)
https://hal.archives-ouvertes.fr/hal-00404129

2002


A neural network simulation system using conductance-based neuromorphic VLSI neurons
Alvado, Ludovic ; Renaud, Sylvie ; Douence, Vincent ; Tomas, Jean ; Lefranc, Yann ; Le Masson, Gwendal
Dans : CCNS'2002, (United States)
https://hal.archives-ouvertes.fr/hal-00203955

1996


Determination of critical process steps for enhanced yield improvement
Duluc, J. ; Zimmer, Thomas ; Lewis, N. ; Dom, Jean
Dans : Microelectronic Manufacturing 1996, Austin (France)
https://hal.archives-ouvertes.fr/hal-01721693

Method for determining the effective base resistance of bipolar transistors
Zimmer, T. ; Berkner, J. ; Branciard, B. ; Lewis, N. ; Duluc, J.B. ; Dom, J.P.
Dans : 1996 BIPOLAR/BiCMOS Circuits and Technology Meeting, Minneapolis (France)
https://hal.archives-ouvertes.fr/hal-01721689
Conférences invitées → 6 Voir

2013


Systèmes Embarqués pour la Santé - Enjeux et applications
Lewis, Noëlle
Dans : Journées Electronique du Club EEA " Electronique et Santé ", (France)
https://hal.archives-ouvertes.fr/hal-00986330

Integrated circuits and systems interacting with biology: exploring mechanisms and therapeutic closed loop paradigms
Lewis, Noëlle
Dans : SEMBA & BioPro International Workshop, Special Session Novel prosthetic Devices, (Taiwan)
https://hal.archives-ouvertes.fr/hal-00986325

2011


Technologies for VLSI Spiking Neural Networks
Renaud, Sylvie
Dans : 2011 International Joint Conference on Neural Networks, San Jose (United States)
https://hal.archives-ouvertes.fr/hal-00677796

2010


Hardware spiking neural networks : models and experiments at the cellular level
Renaud, Sylvie
Dans : Frontiers in neuromorphic computation, Paris (France)
https://hal.archives-ouvertes.fr/hal-00495330

2009


Spiking Neural Network Hardware implementation : from single neurons to networks
Lewis, Noëlle ; Bornat, Yannick ; Renaud, Sylvie
Dans : in NeuroComp'09, Conférence de Neurosciences Computationnelles, Bordeaux (France)
https://hal.archives-ouvertes.fr/hal-00986320

Hybrid neural networks at the neuron (cell) level
Renaud, Sylvie
Dans : International workshop on neuromorphic systems & neural prosthesis, (Taiwan)
https://hal.archives-ouvertes.fr/hal-00551729
Chapitres d'ouvrages scientifiques → 3 Voir

2018


Fabrication of biomolecule microarrays for cell immobilization using automated microcontact printing
Foncy, Julie ; Estève, Aurore ; Degache, Amélie ; Colin, Camille ; Cau, Jean-Chistophe ; Malaquin, Laurent ; Vieu, Christophe ; Trévisiol, Emmanuelle
https://hal.laas.fr/hal-01613897

2011


BioElectronic sensing for insulin demand
Raoux, Matthieu ; Bontorin, Guilherme ; Bornat, Yannick ; Lang, Jochen ; Renaud, Sylvie
https://hal.archives-ouvertes.fr/hal-00667643

2008


Neuromimetic Integrated Circuits
Levi, Timothée ; Lewis, N. ; SaÏghi, S. ; Tomas, J. ; Bornat, Y. ; Renaud, S.
https://hal.archives-ouvertes.fr/hal-00319278
Habilitation à diriger des recherches → 1 Voir

2010


Méthodes de conception des circuits intégrés analogiques et mixtes - Perspectives sur les systèmes électroniques en interaction avec le vivant
Lewis, Noëlle
https://tel.archives-ouvertes.fr/tel-01015800
Preprint, Working Paper, Document sans référence, etc. → 7 Voir

2010


Analog/digital and hybrid bio-silicon circuits for hardware neurons, synapses, and spiking neural netwoks
Indiveri, Giacomo ; Renaud, Sylvie
https://hal.archives-ouvertes.fr/hal-00495319

2006


Hardware specifications for the next generation of neural ASIC Circuits
Tomas, J. ; Renaud, S. ; Destexhe, A.
https://hal.archives-ouvertes.fr/hal-00288470

"Hardware specifications for the next generation of neural ASIC Circuits"
Tomas, J. ; Renaud, S. ; Destexhe, A.
https://hal.archives-ouvertes.fr/hal-00181337

2005


The mixed A/D simulation system of biomimetic neurons: PAX2
Bornat, Y. ; Alvado, L. ; Lopez, C. ; Renaud, S. ; Saighi, S. ; Tomas, Jean
https://hal.archives-ouvertes.fr/hal-00326014

SenseMaker EU project - IST-2001-34712
Mc Ginnity, M. ; Frégnac, Yves ; Meier, Kh. ; Newell, F. ; Renaud, Sylvie
https://hal.archives-ouvertes.fr/hal-00326027

Differential diagnostic between biological and SMU platforms models
Renaud, S. ; Tomas, J. ; Saighi, S.
https://hal.archives-ouvertes.fr/hal-00326016

Technical report of the final closed-loop set up prototype
Renaud, S. ; Tomas, J. ; Alvado, L. ; Lopez, C. ; Bornat, Y. ; Saighi, S.
https://hal.archives-ouvertes.fr/hal-00326015
Brevets → 1 Voir

2011


Sensor for measuring the activity of beta-pancreatic cells or of islets of Langerhans, manufacture and use of such a sensor
Lang, Jochen ; Catargi, Bogdan ; Renaud, Sylvie ; Raoux, Matthieu ; Charpentier, Gilles ; Bornat, Yannick
https://hal.archives-ouvertes.fr/hal-00667612
Theses → 7 Voir

2015


Embedded systems for the interfacing of electronics and biology : modeling and designing an analog adaptive detection chain
Rummens, François
https://tel.archives-ouvertes.fr/tel-01294213

Embedded systems for the interfacing of electronics and biology : modeling and designing an analog adaptive detection chain
Rummens, François
https://tel.archives-ouvertes.fr/tel-01266670

2014


Design of electrical adaptive stimulators for different pathological contexts : a global approach
Kölbl, Florian
https://tel.archives-ouvertes.fr/tel-01191392

2012


Systems and methods for adaptive and real-time detection of biological activity
Quotb, Adam
https://tel.archives-ouvertes.fr/tel-00762842

2011


Real Time Integrated Circuits for Recording and Analysing Local Field Potentials. Application to Parkinson Disease for New Adaptative Deep Brain Stimulation
Zbrzeski, Adeline
https://tel.archives-ouvertes.fr/tel-00674478

2010


Intelligent multielectrode arrays: improving spatiotemporal performances in hybrid (living-artificial), real-time, closed-loop systems
Bontorin, Guilherme
https://tel.archives-ouvertes.fr/tel-00561026

2006


Réseaux de neurones sur silicium : une approche mixte, analogique / numérique, pour l'étude des phénomènes d'adaptation, d'apprentissage et de plasticité
Bornat, Yannick
https://tel.archives-ouvertes.fr/tel-00181353